Well no exact thoughts as I don’t know what you already tried until now.
Here follows some obvious stuff perhaps:
>Have you tried a different USB-3 port?
>Is there enough power for the USB-3 port?
>MB firmware and USB Driver controllers up to date?
Cant think of a couple other ones but these are to obvious perhaps.
From experience I found that USB3 hubs and ports can be dodgy at times, and because not many products NEED USB3 yet and thus you mostly use it as a USB3 it can take a long while for you notice it is not working properly.